Anandamide elicits an acute release of nitric oxide through endothelial TRPV1 receptor activation in the rat arterial mesenteric bed

In the isolated rat mesenteric bed, the 1 min perfusion with 100 nm anandamide, a concentration that did not evoke vasorelaxation, elicited an acute release of 165.1 ± 9.2 pmol nitric oxide (NO) that was paralleled by a 2-fold increase in cGMP tissue levels. The rise in NO released was mimicked by e...

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Autors principals: Poblete, Inés M, Orliac, María Luz, Briones, René, Adler-Graschinsky, Edda, Huidobro-Toro, J Pablo
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2005
Matèries:
Tissue, System and Organ Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474725/
https://ncbi.nlm.nih.gov/pubmed/16081483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.094292
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