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Assessing the effects of metabolism of environmental agents on cancer tumor development by a two-stage model of carcinogenesis.

By combining the Michaelis-Menten kinetics of metabolism with the two-stage model of Moolgavkar and Knudson (1981) and the extended two-stage model of carcinogenesis proposed by Tan and Gastardo (1985), this paper proceeds to investigate the effects of metabolism of carcinogens on cancer tumor devel...

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Autors principals: Tan, W Y, Singh, K P
Format: Artigo
Idioma:Inglês
Publicat: 1987
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474501/
https://ncbi.nlm.nih.gov/pubmed/3691427
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