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Cruciform-extruding regulatory element controls cell-specific activity of the tyrosine hydroxylase gene promoter.

Tyrosine hydroxylase (TH) is expressed specifically in catecholaminergic cells. We have identified a novel regulatory sequence in the upstream region of the bovine TH gene promoter formed by a dyad symmetry element (DSE1;-352/-307 bp). DSE1 supports TH promoter activity in TH-expressing bovine adren...

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Autors principals: Kim, E L, Peng, H, Esparza, F M, Maltchenko, S Z, Stachowiak, M K
Format: Artigo
Idioma:Inglês
Publicat: 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC147441/
https://ncbi.nlm.nih.gov/pubmed/9512554
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