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Proton modulation of recombinant GABA(A) receptors: influence of GABA concentration and the β subunit TM2–TM3 domain

Regulation of GABA(A) receptors by extracellular pH exhibits a dependence on the receptor subunit composition. To date, the molecular mechanism responsible for the modulation of GABA(A) receptors at alkaline pH has remained elusive. We report here that the GABA-activated current can be potentiated a...

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Detalhes bibliográficos
Main Authors: Wilkins, Megan E, Hosie, Alastair M, Smart, Trevor G
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474194/
https://ncbi.nlm.nih.gov/pubmed/15946973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.088823
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