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Increased uncoupling protein-2 mRNA abundance and glucocorticoid action in adipose tissue in the sheep fetus during late gestation is dependent on plasma cortisol and triiodothyronine

The endocrine regulation of uncoupling protein-2 (UCP2), an inner mitochondrial protein, in fetal adipose tissue remains unclear. The present study aimed to determine if fetal plasma cortisol and triiodothyronine (T(3)) influenced the mRNA abundance of UCP2, glucocorticoid receptor (GR) and 11β-hydr...

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Detalhes bibliográficos
Main Authors: Gnanalingham, MG, Mostyn, A, Forhead, AJ, Fowden, AL, Symonds, ME, Stephenson, T
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474155/
https://ncbi.nlm.nih.gov/pubmed/15961419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.091223
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