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Differentiating structural isomers of sialylated glycans by matrix-assisted laser desorption/ionization time-of-flight/time-of-flight tandem mass spectrometry

Using model acidic glycans, we demonstrate the benefits of permethylation for matrix-assisted laser desorption/ionization time-of-flight/time-of-flight (MALDI/TOF-TOF) tandem mass spectrometry. With both the linear and branched structures, extensive cross-ring fragmentation product ions were generat...

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Detalhes bibliográficos
Main Authors: Mechref, Yehia, Kang, Pilsoo, Novotny, Milos V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474049/
https://ncbi.nlm.nih.gov/pubmed/16557638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rcm.2445
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