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Fine-Mapping Chromosome 20 in 230 Systemic Lupus Erythematosus Sib Pair and Multiplex Families: Evidence for Genetic Epistasis with Chromosome 16q12

The presence of systemic lupus erythematosus (SLE) susceptibility genes on chromosome 20 is suggested by the observation of genetic linkage in several independent SLE family collections. To further localize the genetic effects, we typed 59 microsatellites in the two best regions, as defined by genom...

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Autori principali: Gaffney, Patrick M., Langefeld, Carl D., Graham, Robert R., Ortmann, Ward A., Williams, Adrienne H., Rodine, Peter R., Moser, Kathy L., Behrens, Timothy W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society of Human Genetics 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474034/
https://ncbi.nlm.nih.gov/pubmed/16642431
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