Comparative mutagenicities of N6-methoxy-2,6-diaminopurine and N6-methoxyaminopurine 2'-deoxyribonucleosides and their 5'-triphosphates.

The structure of the deoxyribonucleoside derived from N 6-methoxy-2, 6-diaminopurine (dK) was examined by NMR. The methoxyamino residue was found predominantly in the imino rather than the amino tautomer (ratio: 9:1 in DMSO). The nucleoside proved to be a potent transition mutagen in Escherichia col...

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Bibliographic Details

Published in:	Nucleic Acids Res
Main Authors:	Hill, F, Williams, D M, Loakes, D, Brown, D M
Format:	Artigo
Language:	Inglês
Published:	Oxford University Press 1998
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147402/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9469819/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.5.1144
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