A central region of Ku80 mediates interaction with Ku70 in vivo.
Ku, the DNA binding component of DNA-dependent protein kinase (DNA-PK), is a heterodimer composed of 70 and 86 kDa subunits, known as Ku70 and Ku80 respectively . Defects in DNA-PK subunits have been shown to result in a reduced capacity to repair DNA double-strand breaks. Assembly of the Ku heterod...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
1998
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147353/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9461456/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.4.974 |
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