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Amplification of closed circular DNA in vitro.

The polymerase chain reaction is a powerful technique used to amplify nucleic acids in vitro . The reaction produces linear products, and as of yet, closed circular products have not been possible. Since the replicatively competent form of many DNA molecules is the closed circular form, it would be...

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Detalles Bibliográficos
Main Authors: Chen, Z, Ruffner, D E
Formato: Artigo
Idioma:Inglês
Publicado: 1998
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC147341/
https://ncbi.nlm.nih.gov/pubmed/9461478
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