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High and low affinity Ca2+ binding to the sarcoplasmic reticulum: use of a high-affinity fluorescent calcium indicator.

The fluorescent calcium indicator, calcein, has been used as a high-affinity indicator of Ca2+ in the aqueous phase at physiological pH in the study of high-affinity calcium binding to sarcoplasmic reticulum (SR). The binding constant of the indicator at physiological pH is 10(3)-10(4) M-1 and incre...

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Bibliographic Details
Main Authors: Chiu, V C, Haynes, D H
Format: Artigo
Language:Inglês
Published: 1977
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1473279/
https://ncbi.nlm.nih.gov/pubmed/15667
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