Solution structure of the novel antitumor drug UCH9 complexed with d(TTGGCCAA)2 as determined by NMR.

Aureolic acid group compounds, such as chromomycin A3(CHM) and mithramycin (MIT), are known as antitumor drugs. Recently we isolated a novel aureolic acid group antitumor drug, UCH9, from Streptomyces sp. The chemical structure of UCH9 is unique in that mono- (A ring) and tetrasaccharide (B-E rings)...

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Dettagli Bibliografici

Pubblicato in:	Nucleic Acids Res
Autori principali:	Katahira, R, Katahira, M, Yamashita, Y, Ogawa, H, Kyogoku, Y, Yoshida, M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1998
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147319/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9443966/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.3.744
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