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Evolutionary turnover of mammalian transcription start sites

Alignments of homologous genomic sequences are widely used to identify functional genetic elements and study their evolution. Most studies tacitly equate homology of functional elements with sequence homology. This assumption is violated by the phenomenon of turnover, in which functionally equivalen...

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Detalhes bibliográficos
Main Authors: Frith, Martin C., Ponjavic, Jasmina, Fredman, David, Kai, Chikatoshi, Kawai, Jun, Carninci, Piero, Hayshizaki, Yoshihide, Sandelin, Albin
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1473182/
https://ncbi.nlm.nih.gov/pubmed/16687732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.5031006
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