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How reliable are empirical genomic scans for selective sweeps?

The beneficial substitution of an allele shapes patterns of genetic variation at linked sites. Thus, in principle, adaptations can be mapped by looking for the signature of directional selection in polymorphism data. In practice, such efforts are hampered by the need for an accurate characterization...

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Détails bibliographiques
Auteurs principaux: Teshima, Kosuke M., Coop, Graham, Przeworski, Molly
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1473181/
https://ncbi.nlm.nih.gov/pubmed/16687733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.5105206
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