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Sp1 activation of a TATA-less promoter requires a species-specific interaction involving transcription factor IID.

Sp1 is a ubiquitous activator of numerous TATA-containing and TATA-less promoters within the human genome. This transcription factor is distinct from several other mammalian activators because it cannot stimulate transcription of reporter genes when ectopically expressed in Saccharomyces cerevisiae...

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Détails bibliographiques
Auteurs principaux: Emami, K H, Burke, T W, Smale, S T
Format: Artigo
Langue:Inglês
Publié: 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC147315/
https://ncbi.nlm.nih.gov/pubmed/9443978
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