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The proximal sequence element (PSE) plays a major role in establishing the RNA polymerase specificity of Drosophila U-snRNA genes.

Most small nuclear RNA (snRNA) genes are transcribed by RNA polymerase II, but some (e.g., U6) are transcribed by RNA polymerase III. In vertebrates a TATA box at a fixed distance downstream of the proximal sequence element (PSE) acts as a dominant determinant for recruiting RNA polymerase III to U6...

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Pubblicato in:Nucleic Acids Res
Autori principali: Jensen, R C, Wang, Y, Hardin, S B, Stumph, W E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 1998
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147272/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9421524/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.2.616
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