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CXCL16-Mediated Cell Recruitment to Rheumatoid Arthritis Synovial Tissue and Murine Lymph Nodes Is Dependent Upon the MAPK Pathway

OBJECTIVE: Rheumatoid arthritis (RA) is characterized by profound mononuclear cell (MNC) recruitment into synovial tissue (ST), thought to be due in part to tumor necrosis factor α (TNFα), a therapeutic target for RA. Although chemokines may also be involved, the mechanisms remain unclear. We undert...

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Autors principals: Ruth, Jeffrey H., Haas, Christian S., Park, Christy C., Amin, M. Asif, Martinez, Rita J., Haines, G. Kenneth, Shahrara, Shiva, Campbell, Phillip L., Koch, Alisa E.
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472704/
https://ncbi.nlm.nih.gov/pubmed/16508941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.21662
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