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Bioinformatics and Multiepitope DNA Immunization to Design Rational Snake Antivenom

BACKGROUND: Snake venom is a potentially lethal and complex mixture of hundreds of functionally diverse proteins that are difficult to purify and hence difficult to characterize. These difficulties have inhibited the development of toxin-targeted therapy, and conventional antivenom is still generate...

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Detalhes bibliográficos
Main Authors: Wagstaff, Simon C, Laing, Gavin D, Theakston, R. David G, Papaspyridis, Christina, Harrison, Robert A
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472699/
https://ncbi.nlm.nih.gov/pubmed/16737347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0030184
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