Molecular and Functional Analyses of a Human Parvovirus B19 Infectious Clone Demonstrates Essential Roles for NS1, VP1, and the 11-Kilodalton Protein in Virus Replication and Infectivity

In an attempt to experimentally define the roles of viral proteins encoded by the B19 genome in the viral life cycle, we utilized the B19 infectious clone constructed in our previous study to create two groups of B19 mutant genomes: (i) null mutants, in which either a translational initiation codon...

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Detalhes bibliográficos
Main Authors: Zhi, Ning, Mills, Ian P., Lu, Jun, Wong, Susan, Filippone, Claudia, Brown, Kevin E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472615/
https://ncbi.nlm.nih.gov/pubmed/16731932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02430-05
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