Deregulation of DNA Damage Signal Transduction by Herpesvirus Latency-Associated M2

Infected cells recognize viral replication as a DNA damage stress and elicit a DNA damage response that ultimately induces apoptosis as part of host immune surveillance. Here, we demonstrate a novel mechanism where the murine gamma herpesvirus 68 (γHV68) latency-associated, anti-interferon M2 protei...

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Autors principals: Liang, Xiaozhen, Pickering, Mary T., Cho, Nam-Hyuk, Chang, Heesoon, Volkert, Michael R., Kowalik, Timothy F., Jung, Jae U.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
Matèries:
Virus-Cell Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472574/
https://ncbi.nlm.nih.gov/pubmed/16731925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02732-05
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