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Sindbis Virus Nonstructural Protein nsP2 Is Cytotoxic and Inhibits Cellular Transcription

Replication of alphaviruses in vertebrate cells strongly affects cell physiology and ultimately leads to development of a cytopathic effect (CPE) and cell death. Sindbis virus (SIN) replication causes major changes in cellular macromolecular synthesis, in which the strong downregulation of transcrip...

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Autors principals: Garmashova, Natalia, Gorchakov, Rodion, Frolova, Elena, Frolov, Ilya
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472573/
https://ncbi.nlm.nih.gov/pubmed/16731907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02739-05
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