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Elimination of damaged proteins during differentiation of embryonic stem cells

During mammalian aging, cellular proteins become increasingly damaged: for example, by carbonylation and formation of advanced glycation end products (AGEs). The means to ensure that offspring are born without such damage are unknown. Unexpectedly, we found that undifferentiated mouse ES cells conta...

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Detalhes bibliográficos
Main Authors: Hernebring, Malin, Brolén, Gabriella, Aguilaniu, Hugo, Semb, Henrik, Nyström, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472508/
https://ncbi.nlm.nih.gov/pubmed/16672370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510944103
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