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A mitotic topoisomerase II checkpoint in budding yeast is required for genome stability but acts independently of Pds1/securin

Topoisomerase II (Topo II) performs topological modifications on double-stranded DNA molecules that are essential for chromosome condensation, resolution, and segregation. In mammals, G2 and metaphase cell cycle delays induced by Topo II poisons have been proposed to be the result of checkpoint acti...

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Detalhes bibliográficos
Main Authors: Andrews, Catherine A., Vas, Amit C., Meier, Brian, Giménez-Abián, Juan F., Díaz-Martínez, Laura A., Green, Julie, Erickson, Stacy L., VanderWaal, Kristyn E., Hsu, Wei-Shan, Clarke, Duncan J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472475/
https://ncbi.nlm.nih.gov/pubmed/16651657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1367206
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