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A mitotic topoisomerase II checkpoint in budding yeast is required for genome stability but acts independently of Pds1/securin
Topoisomerase II (Topo II) performs topological modifications on double-stranded DNA molecules that are essential for chromosome condensation, resolution, and segregation. In mammals, G2 and metaphase cell cycle delays induced by Topo II poisons have been proposed to be the result of checkpoint acti...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Cold Spring Harbor Laboratory Press
2006
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1472475/ https://ncbi.nlm.nih.gov/pubmed/16651657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1367206 |
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