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Requirement of clathrin heavy chain for p53-mediated transcription
The p53 protein is a transcription factor that activates various genes responsible for growth arrest and/or apoptosis in response to DNA damage. Here, we report that clathrin heavy chain (CHC) binds to p53 and contributes to p53-mediated transcription. CHC is known to be a cytosolic protein that fun...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1472469/ https://ncbi.nlm.nih.gov/pubmed/16618797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1381906 |
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