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Repression of Flt3 by Pax5 is crucial for B-cell lineage commitment
Early B-lymphopoiesis requires the growth-factor receptors, IL-7R and Flt3, and the activity of a number of transcription factors. One factor, Pax5, is required for commitment to the B-cell lineage, although the molecular mechanism by which this occurs is unknown. We demonstrate here that an importa...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Cold Spring Harbor Laboratory Press
2006
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1472301/ https://ncbi.nlm.nih.gov/pubmed/16618805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1396206 |
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