PIAS1 confers DNA-binding specificity on the Msx1 homeoprotein

The mechanisms by which homeoproteins bind selectively to target genes in vivo have long remained unresolved. Here we report that PIAS1 confers DNA-binding specificity on the Msx1 homeoprotein by regulating its subnuclear localization and proximity to target genes. We demonstrate that the interactio...

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Detalhes bibliográficos
Main Authors: Lee, Hansol, Quinn, John C., Prasanth, Kannanganattu V., Swiss, Victoria A., Economides, Kyriakos D., Camacho, Marie M., Spector, David L., Abate-Shen, Cory
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472282/
https://ncbi.nlm.nih.gov/pubmed/16600910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1392006
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