7-O-Malonyl Macrolactin A, a New Macrolactin Antibiotic from Bacillus subtilis Active against Methicillin-Resistant Staphylococcus aureus, Vancomycin-Resistant Enterococci, and a Small-Colony Variant of Burkholderia cepacia

We report here the discovery, isolation, and chemical and preliminary biological characterization of a new antibiotic compound, 7-O-malonyl macrolactin A (MMA), produced by a Bacillus subtilis soil isolate. MMA is a bacteriostatic antibiotic that inhibits a number of multidrug-resistant gram-positiv...

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Detalhes bibliográficos
Main Authors: Romero-Tabarez, Magally, Jansen, Rolf, Sylla, Marita, Lünsdorf, Heinrich, Häußler, Susanne, Santosa, Dwi A., Timmis, Kenneth N., Molinari, Gabriella
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472237/
https://ncbi.nlm.nih.gov/pubmed/16641438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.5.1701-1709.2006
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