Long-Term Multiple-Dose Pharmacokinetics of Human Monoclonal Antibodies (MAbs) against Human Immunodeficiency Virus Type 1 Envelope gp120 (MAb 2G12) and gp41 (MAbs 4E10 and 2F5)

While certain antibodies directed against the human immunodeficiency virus (HIV) envelope have the potential to suppress virus replication in vitro, the impact of neutralizing antibodies in vivo remains unclear. In a recent proof-of-concept study, the broadly neutralizing monoclonal antibodies 2G12,...

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Autors principals: Joos, Beda, Trkola, Alexandra, Kuster, Herbert, Aceto, Leonardo, Fischer, Marek, Stiegler, Gabriela, Armbruster, Christine, Vcelar, Brigitta, Katinger, Hermann, Günthard, Huldrych F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
Matèries:
Clinical Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472186/
https://ncbi.nlm.nih.gov/pubmed/16641449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.5.1773-1779.2006
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