Diversity of the CD8(+) T-Cell Response to Herpes Simplex Virus Type 2 Proteins among Persons with Genital Herpes

Cytolytic T cells play a major role in controlling herpes simplex virus type 2 (HSV-2) infections in humans. In an effort to more thoroughly evaluate the response to HSV-2 directly, ex vivo, we developed an enzyme-linked immunospot (ELISPOT) assay that utilized pools of overlapping synthetic peptide...

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Bibliographic Details
Main Authors: Hosken, Nancy, McGowan, Patrick, Meier, Amalia, Koelle, David M., Sleath, Paul, Wagener, Felecia, Elliott, Mark, Grabstein, Ken, Posavad, Christine, Corey, Lawrence
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472180/
https://ncbi.nlm.nih.gov/pubmed/16699031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02659-05
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