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Phase I Evaluation of Intranasal Trivalent Inactivated Influenza Vaccine with Nontoxigenic Escherichia coli Enterotoxin and Novel Biovector as Mucosal Adjuvants, Using Adult Volunteers

Trivalent influenza virus A/Duck/Singapore (H5N3), A/Panama (H3N2), and B/Guandong vaccine preparations were used in a randomized, controlled, dose-ranging phase I study. The vaccines were prepared from highly purified hemagglutinin and neuraminidase from influenza viruses propagated in embryonated...

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Detalhes bibliográficos
Main Authors: Stephenson, Iain, Zambon, Maria C., Rudin, Anna, Colegate, Anthony, Podda, Audino, Bugarini, Roberto, del Giudice, Giusseppe, Minutello, Ada, Bonnington, Susan, Holmgren, Jan, Mills, Kingston H. G., Nicholson, Karl G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472052/
https://ncbi.nlm.nih.gov/pubmed/16641287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.10.4962-4970.2006
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