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Modification of human U4 RNA requires U6 RNA and multiple pseudouridine synthases.

Small nuclear RNAs (snRNA), cofactors in the splicing of pre-mRNA, are highly modified. In this report the modification of human U4 RNA was studied using cell extracts and in vitro synthesized, and therefore unmodified, U4 RNA. The formation of pseudouridine (Psi) at positions 4, 72 and 79 in U4 RNA...

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Udgivet i:Nucleic Acids Res
Principais autores: Zerby, D B, Patton, J R
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147118/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9365261/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.23.4808
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