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Application of coalescent methods to reveal fine-scale rate variation and recombination hotspots.

There has been considerable recent interest in understanding the way in which recombination rates vary over small physical distances, and the extent of recombination hotspots, in various genomes. Here we adapt, apply, and assess the power of recently developed coalescent-based approaches to estimati...

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Detalhes bibliográficos
Main Authors: Fearnhead, Paul, Harding, Rosalind M, Schneider, Julie A, Myers, Simon, Donnelly, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1470991/
https://ncbi.nlm.nih.gov/pubmed/15342541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.103.021584
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