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Estimating the frequency of events that cause multiple-nucleotide changes.

Existing mathematical models of DNA sequence evolution assume that all substitutions derive from point mutations. There is, however, increasing evidence that larger-scale events, involving two or more consecutive sites, may also be important. We describe a model, denoted SDT, that allows for single-...

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Detalhes bibliográficos
Main Authors: Whelan, Simon, Goldman, Nick
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1470989/
https://ncbi.nlm.nih.gov/pubmed/15342538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.103.023226
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