Nalaganje...
Genome-wide patterns of nucleotide substitution reveal stringent functional constraints on the protein sequences of thermophiles.
To test the hypothesis that the proteins of thermophilic prokaryotes are subject to unusually stringent functional constraints, we estimated the numbers of synonymous and nonsynonymous nucleotide substitutions per site between 17,957 pairs of orthologous genes from 22 pairs of closely related specie...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1470942/ https://ncbi.nlm.nih.gov/pubmed/15280258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.026344 |
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