Modification of an existing chromosomal inversion to engineer a balancer for mouse chromosome 15.

Chromosomal inversions are valuable genetic tools for mutagenesis screens, where appropriately marked inversions can be used as balancer chromosomes to recover and maintain mutations in the corresponding chromosomal region. For any inversion to be effective as a balancer, it should exhibit both domi...

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Bibliographic Details
Main Authors: Chick, Wallace S H, Mentzer, Sarah E, Carpenter, Donald A, Rinchik, Eugene M, You, Yun
Format: Artigo
Language:Inglês
Published: 2004
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1470889/
https://ncbi.nlm.nih.gov/pubmed/15238537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.026468
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