A large-scale screen for mutagen-sensitive loci in Drosophila.

In a screen for new DNA repair mutants, we tested 6275 Drosophila strains bearing homozygous mutagenized autosomes (obtained from C. Zuker) for hypersensitivity to methyl methanesulfonate (MMS) and nitrogen mustard (HN2). Testing of 2585 second-chromosome lines resulted in the recovery of 18 mutants...

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Detalhes bibliográficos
Main Authors: Laurencon, Anne, Orme, Charisse M, Peters, Heather K, Boulton, Christina L, Vladar, Eszter K, Langley, Sasha A, Bakis, Emmanuel P, Harris, David T, Harris, Nathan J, Wayson, Sarah M, Hawley, R Scott, Burtis, Kenneth C
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1470880/
https://ncbi.nlm.nih.gov/pubmed/15166149
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