Genetic interactions with C-terminal domain (CTD) kinases and the CTD of RNA Pol II suggest a role for ESS1 in transcription initiation and elongation in Saccharomyces cerevisiae.

Ess1 is an essential prolyl isomerase that binds the C-terminal domain (CTD) of Rpb1, the large subunit of RNA polymerase II. Ess1 is proposed to control transcription by isomerizing phospho-Ser-Pro peptide bonds within the CTD repeat. To determine which step(s) in the transcription cycle might requ...

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Detalles Bibliográficos
Autores principales: Wilcox, Cathy B, Rossettini, Anne, Hanes, Steven D
Formato: Artigo
Lenguaje:Inglês
Publicado: 2004
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1470855/
https://ncbi.nlm.nih.gov/pubmed/15166139
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