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Binding of Hoechst 33258 to the TAR RNA of HIV-1. Recognition of a pyrimidine bulge-dependent structure.

The transactivation response region (TAR) RNA is an essential component in transcriptional regulation of the human immunodeficiency virus type-1 (HIV-1) genome. We have examined the interaction between TAR RNA and the bisbenzimidazole derivative Hoechst 33258. Previous studies have shown that this d...

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Udgivet i:Nucleic Acids Res
Principais autores: Dassonneville, L, Hamy, F, Colson, P, Houssier, C, Bailly, C
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147084/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9358156/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.22.4487
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