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Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2

The transition to pulmonary respiration following birth requires rapid alterations in the structure of the mammalian cardiovascular system. One dramatic change that occurs is the closure and remodeling of the ductus arteriosus (DA), an arterial connection in the fetus that directs blood flow away fr...

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Published in:Proc Natl Acad Sci U S A
Main Authors: Loftin, Charles D., Trivedi, Darshini B., Tiano, Howard F., Clark, James A., Lee, Christopher A., Epstein, Jonathan A., Morham, Scott G., Breyer, Matthew D., Nguyen, MyTrang, Hawkins, Beau M., Goulet, Jennifer L., Smithies, Oliver, Koller, Beverly H., Langenbach, Robert
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2001
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14708/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11158594/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.031573498
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