Peptide nucleic acid-anthraquinone conjugates: strand invasion and photoinduced cleavage of duplex DNA.

A bis-peptide nucleic acid (PNA)-anthraquinone imide (AQI) conjugate has been synthesized and shown to form strand invasion complexes with a duplex DNA target. The two arms of the bis-PNA each consist of five consecutive thymine residues and are linked by a flexible, hydrophilic spacer. Probing with...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Armitage, B, Koch, T, Frydenlund, H, Orum, H, Batz, H G, Schuster, G B
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147076/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9358181/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.22.4674
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