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The yeast 8-oxoguanine DNA glycosylase (Ogg1) contains a DNA deoxyribophosphodiesterase (dRpase) activity.

The yeast OGG1 gene was recently cloned and shown to encode a protein that possesses N-glycosylase/AP lyase activities for the repair of oxidatively damaged DNA at sites of 7,8-dihydro-8-oxoguanine (8-oxoguanine). Similar activities have been identified for Escherichia coli formamidopyrimidine-DNA g...

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Publicat a:Nucleic Acids Res
Autors principals: Sandigursky, M, Yacoub, A, Kelley, M R, Xu, Y, Franklin, W A, Deutsch, W A
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147074/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9358166/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.22.4557
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