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A synthetic lethal screen identifies a role for the cortical actin patch/endocytosis complex in the response to nutrient deprivation in Saccharomyces cerevisiae.

Saccharomyces cerevisiae whi2Delta cells are unable to halt cell division in response to nutrient limitation and are sensitive to a wide variety of stresses. A synthetic lethal screen resulted in the isolation of siw mutants that had a phenotype similar to that of whi2Delta. Among these were mutatio...

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Auteurs principaux: Care, Alison, Vousden, Katherine A, Binley, Katie M, Radcliffe, Pippa, Trevethick, Janet, Mannazzu, Ilaria, Sudbery, Peter E
Format: Artigo
Langue:Inglês
Publié: 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1470737/
https://ncbi.nlm.nih.gov/pubmed/15020461
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