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Recovery of Visual Functions in a Mouse Model of Leber Congenital Amaurosis
The visual process is initiated by the photoisomerization of 11-cis-retinal to all-trans-retinal. For sustained vision the 11-cis-chromophore must be regenerated from all-trans-retinal. This requires RPE65, a dominant retinal pigment epithelium protein. Disruption of the RPE65 gene results in massiv...
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| Main Authors: | , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2002
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1470660/ https://ncbi.nlm.nih.gov/pubmed/11897783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112384200 |
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