Recovery of Visual Functions in a Mouse Model of Leber Congenital Amaurosis

The visual process is initiated by the photoisomerization of 11-cis-retinal to all-trans-retinal. For sustained vision the 11-cis-chromophore must be regenerated from all-trans-retinal. This requires RPE65, a dominant retinal pigment epithelium protein. Disruption of the RPE65 gene results in massiv...

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Bibliografiske detaljer
Main Authors: Van Hooser, J. Preston, Liang, Yan, Maeda, Tadao, Kuksa, Vladimir, Jang, Geeng-Fu, He, Yu-Guang, Rieke, Fred, Fong, Henry K. W., Detwiler, Peter B., Palczewski, Krzysztof
Format: Artigo
Sprog:Inglês
Udgivet: 2002
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1470660/
https://ncbi.nlm.nih.gov/pubmed/11897783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112384200
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