The efficiency of a cis-cleaving ribozyme in an mRNA coding region is influenced by the translating ribosome in vivo.

A cis -cleaving hammerhead ribozyme (Rz) expression system (3A'-Rz) in Escherichia coli has been constructed that can be used to study the involvement of factors that affect ribozyme cleavage in vivo . The ribozyme sequence is placed in the coding region of 3A' mRNA, which is expressed from a semi-s...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Zhang, S, Stancek, M, Isaksson, L A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147047/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9336461/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.21.4301
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