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A rapid RT-PCR based method to isolate complementary DNA fragments flanking retrovirus integration sites.

Proto-oncogenes in retrovirally induced myeloid mouse leukemias are frequently activated following retroviral insertion. The identification of common virus integration sites (VISs) and isolation of the transforming oncogene is laborious and time consuming. We established a rapid and simple PCR based...

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Bibliografiske detaljer
Main Authors: Valk, P J, Joosten, M, Vankan, Y, Löwenberg, B, Delwel, R
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC147027/
https://ncbi.nlm.nih.gov/pubmed/9336478
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