The primer binding site on the RNA genome of human and simian immunodeficiency viruses is flanked by an upstream hairpin structure.
Reverse transcription of retroviral genomes is primed by a tRNA molecule that anneals to an 18 nt primer binding site (PBS) on the viral RNA genome. Additional base pair interactions between the tRNA primer and the viral RNA have been proposed. In particular, base pairing was proposed between the an...
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| Udgivet i: | Nucleic Acids Res |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1997
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147018/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9321651/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.20.4013 |
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