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Genetic and environmental factors associated with variation of human xenobiotic glucuronidation and sulfation.

Glucuronidation and sulfation are phase 2 metabolic reactions catalyzed by large families of different isoenzymes in man. The textbook view that glucuronidation and sulfation lead to the production of harmless conjugates for simple excretion is not valid. Biologically active and toxic sulfates and g...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Burchell, B, Coughtrie, M W
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1997
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1470020/
https://ncbi.nlm.nih.gov/pubmed/9255555
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