Minor groove binding of a bis-quaternary ammonium compound: the crystal structure of SN 7167 bound to d(CGCGAATTCGCG)2.

The X-ray crystal structure of the complex between the synthetic antitumour and antiviral DNA binding ligand SN 7167 and the DNA oligonucleotide d(CGCGAATTCGCG)2 has been determined to an R factor of 18.3% at 2.6 A resolution. The ligand is located within the minor groove and covers almost 6 bp with...

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Vydáno v:	Nucleic Acids Res
Hlavní autoři:	Squire, C J, Clark, G R, Denny, W A
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Oxford University Press 1997
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146996/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9321660/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.20.4072
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