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Medical hypothesis: bifunctional genetic-hormonal pathways to breast cancer.

As inherited germ line mutations, such as loss of BRCA1 or AT, account for less than 5% of all breast cancer, most cases involve acquired somatic perturbations. Cumulative lifetime exposure to bioavailable estradiol links most known risk factors (except radiation) for breast cancer. Based on a serie...

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Autores principales: Davis, D L, Telang, N T, Osborne, M P, Bradlow, H L
Formato: Artigo
Lenguaje:Inglês
Publicado: 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1469908/
https://ncbi.nlm.nih.gov/pubmed/9167997
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